Effects of Creatine on Strength and Power
A meta-analysis examining upper- and lower-body strength and power outcomes associated with creatine supplementation combined with resistance training.
- Resistance-trained adults
Creatine monohydrate is one of the most extensively studied ingredients in sports nutrition. Research supports its use for improving strength, power and performance during repeated bouts of brief, high-intensity activity. When combined with resistance training, it can also support increases in lean muscle mass.
Product benefits depend on consistent use, individual response and the recommended conditions of use.

You do not need to read hundreds of studies to understand why creatine has become one of the most widely used sports supplements. The strongest evidence can be summarized in three practical benefits.
Creatine can improve strength, power and performance during repeated bouts of brief, high-intensity physical activity.
When combined with resistance training, creatine can support increases in lean muscle mass.
Creatine works through consistent daily use. A loading phase is not required when the product is taken as directed over time.
Researchers continue to study creatine in areas beyond sports performance. These topics are presented for educational purposes and should not be interpreted as approved product claims or guaranteed outcomes.
Researchers are studying whether creatine may influence certain aspects of memory, attention and cognitive performance in specific populations.
Research is exploring how creatine may support strength, function and physical resilience as people age.
Some studies are investigating creatine in relation to exercise recovery, muscle function and rehabilitation.
Early research is examining possible relationships between creatine and additional areas of health. More evidence is needed before broad conclusions can be made.
Purelii does not claim that its creatine product diagnoses, treats, prevents or cures any disease or health condition.
Browse selected peer-reviewed studies and scientific reviews related to creatine. Each summary is provided in plain language, with a direct link to the original source.
Research information is provided for educational purposes and is not a substitute for medical advice.
A meta-analysis examining upper- and lower-body strength and power outcomes associated with creatine supplementation combined with resistance training.
A review of creatine supplementation combined with resistance training and its observed effect on muscle strength across multiple trials.
Read the Original StudyA randomized trial that found improvements in muscle power, endurance and sprint performance in supplemented participants versus control.
A double-blind randomized crossover trial that observed improvements in strength, fatigue resistance and recovery markers with creatine.
A study examining creatine combined with carbohydrate and protein intake in relation to repeated sprint performance outcomes.
Read the Original StudyA meta-analysis suggesting that creatine combined with resistance training can improve lean tissue mass and muscular strength in older adults.
Not every study answers the same question. Results can vary depending on the participants, dosage, duration, exercise program and outcome being measured. Strong conclusions are usually based on multiple well-designed studies rather than a single paper.
The study was evaluated by other qualified experts before publication.
Results in trained athletes, older adults or other specific groups may not apply equally to everyone.
Some effects require weeks of consistent use and may not be noticeable immediately.
Systematic reviews and meta-analyses can provide stronger overall evidence than a single small study.


PURELii believes good science should be understandable, transparent and relevant to everyday people.
Creatine monohydrate is one of the most extensively studied sports supplement ingredients. It is generally well tolerated by healthy adults when used according to the product directions.
Some people may experience temporary digestive discomfort, particularly when taking large amounts at once. Taking the recommended serving with adequate fluid may help improve tolerance.
Consult a healthcare professional before use if you are pregnant or breastfeeding, have a medical condition, take medication or have been advised to restrict your intake of certain nutrients or supplements.
Always follow the directions, cautions and conditions of use printed on the Purelii product label.
Clear answers to common questions about creatine, based on the available evidence and responsible product use.
Pure. Tested. Proudly Canadian. One simple daily serving backed by decades of creatine research.
425 g · Approximately 85 servings · Unflavoured · Third-party tested
Use only as directed. Results vary based on training, nutrition, consistency and individual response.